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Mouse CD133 (aa 20 – 107)

Prom Swiss Prot#

O54990

Prom Protein names

Prominin-1 (Antigen AC133 homolog) (Prominin-like protein 1) (CD antigen CD133)

Prom Gene names

Prom1 Prom Proml1

Organism

Mouse

Prom Entry name

PROM1_MOUSE

Prom Codon optimized cDNA(gene) Clone

Prom Cat #

RPV0120

Tag

Prom contains A 6x histidine tag

Prom Formulation

Liquid

Prom Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Prom Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Prom Protein

Prom Cat #

PV0120

Prom Source

recombinant.

Prom Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Prom Purity

>90%, as determined by SDS-PAGE under reducing conditions

Prom Activity

N/A

Tag

Prom Contains A 6x histidine tag

Prom Formulation

Liquid

Prom Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Prom family

SUBUNIT: Interacts with CDHR1 and with actin filaments (By similarity).

Prom Subcellular locations

SUBCELLULAR LOCATION: Apical cell membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Found in extracellular membrane particles in various body fluids such as ventricular fluid of the developing brain and urine.

Prom FUNCTION According to UniProtKB Swiss Prot

Binds cholesterol in cholesterol-containing plasma membrane microdomains. Proposed to play a role in apical plasma membrane organization of epithelial cells. During early during retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (By similarity).

Prom Sequence

DDBJ

EMBL

GenBank

Prom 3D structure

ModBase

Prom interaction

STRING

Prom Proteomic

PRIDE

Prom Genome annotation

Ensembl

GeneID

KEGG

UCSC

Prom Organism specific

CTD

MGI

Prom Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Prom Gene expression

Bgee

ArrayExpress

Genevestigator

Prom Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY