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Human CD133 (aa 20 – 108)

PROML1 Swiss Prot#

O43490

PROML1 Protein names

Prominin-1 (Antigen AC133) (Prominin-like protein 1) (CD antigen CD133)

PROML1 Gene names

PROM1 PROML1 MSTP061

Organism

Human

PROML1 Entry name

PROM1_HUMAN

PROML1 Codon optimized cDNA(gene) Clone

PROML1 Cat #

RPV0119

Tag

PROML1 contains A 6x histidine tag

PROML1 Formulation

Liquid

PROML1 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PROML1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PROML1 Protein

PROML1 Cat #

PV0119

PROML1 Source

recombinant.

PROML1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PROML1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

PROML1 Activity

N/A

Tag

PROML1 Contains A 6x histidine tag

PROML1 Formulation

Liquid

PROML1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PROML1 family

SUBUNIT: Interacts with CDHR1 and with actin filaments.

PROML1 Subcellular locations

SUBCELLULAR LOCATION: Cell projection, cilium, photoreceptor outer segment (By similarity). ; SUBCELLULAR LOCATION: Isoform 1: Apical cell membrane; Multi-pass membrane protein (By similarity). Cell projection, microvillus membrane; Multi-pass membrane protein (By similarity). Note=Found in extracellular membrane particles in various body fluids such as cerebrospinal fluid, saliva, seminal fluid and urine.

PROML1 FUNCTION According to UniProtKB Swiss Prot

Binds cholesterol in cholesterol-containing plasma membrane microdomains. Proposed to play a role in apical plasma membrane organization of epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

PROML1 Sequence

DDBJ

EMBL

GenBank

PROML1 3D structure

ModBase

PROML1 interaction

STRING

PROML1 Proteomic

PRIDE

PROML1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

PROML1 Organism specific

CTD

MGI

PROML1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PROML1 Gene expression

Bgee

ArrayExpress

Genevestigator

PROML1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY