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Human cd11b (aa 17 – 417)

CD11B Swiss Prot#

P11215

CD11B Protein names

Integrin alpha-M (CD11 antigen-like family member B) (CR-3 alpha chain) (Cell surface glycoprotein MAC-1 subunit alpha) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD antigen CD11b)

CD11B Gene names

ITGAM CD11B CR3A

Organism

Human

CD11B Entry name

ITAM_HUMAN

CD11B Codon optimized cDNA(gene) Clone

CD11B Cat #

RPV0078

Tag

CD11B contains A 6x histidine tag

CD11B Formulation

Liquid

CD11B Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CD11B Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CD11B Protein

CD11B Cat #

PV0078

CD11B Source

recombinant.

CD11B Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CD11B Purity

>90%, as determined by SDS-PAGE under reducing conditions

CD11B Activity

N/A

Tag

CD11B Contains A 6x histidine tag

CD11B Formulation

Liquid

CD11B Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CD11B family

SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-M associates with beta-2. Interacts with JAM3.

CD11B Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

CD11B FUNCTION According to UniProtKB Swiss Prot

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

CD11B Sequence

DDBJ

EMBL

GenBank

CD11B 3D structure

ModBase

CD11B interaction

STRING

CD11B Proteomic

PRIDE

CD11B Genome annotation

Ensembl

GeneID

KEGG

UCSC

CD11B Organism specific

CTD

MGI

CD11B Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CD11B Gene expression

Bgee

ArrayExpress

Genevestigator

CD11B Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY