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Mouse cd11a (aa 153 – 325)

Lfa-1 Swiss Prot#

P24063

Lfa-1 Protein names

Integrin alpha-L (CD11 antigen-like family member A) (Leukocyte adhesion glycoprotein LFA-1 alpha chain) (LFA-1A) (Leukocyte function-associated molecule 1 alpha chain) (Lymphocyte antigen 15) (Ly-15) (CD antigen CD11a)

Lfa-1 Gene names

Itgal Lfa-1 Ly-15

Organism

Mouse

Lfa-1 Entry name

ITAL_MOUSE

Lfa-1 Codon optimized cDNA(gene) Clone

Lfa-1 Cat #

RPV0076

Tag

Lfa-1 contains A 6x histidine tag

Lfa-1 Formulation

Liquid

Lfa-1 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Lfa-1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Lfa-1 Protein

Lfa-1 Cat #

PV0076

Lfa-1 Source

recombinant.

Lfa-1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Lfa-1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Lfa-1 Activity

N/A

Tag

Lfa-1 Contains A 6x histidine tag

Lfa-1 Formulation

Liquid

Lfa-1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Lfa-1 family

SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-L associates with beta-2.

Lfa-1 Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

Lfa-1 FUNCTION According to UniProtKB Swiss Prot

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Mice expressing a null mutation of the alpha-L subunit gene demonstrate impaired tumor rejection and impaired leukocytes recruitment.

Lfa-1 Sequence

DDBJ

EMBL

GenBank

Lfa-1 3D structure

ModBase

Lfa-1 interaction

STRING

Lfa-1 Proteomic

PRIDE

Lfa-1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Lfa-1 Organism specific

CTD

MGI

Lfa-1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Lfa-1 Gene expression

Bgee

ArrayExpress

Genevestigator

Lfa-1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY