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Human cd118 (aa 332– 833)

LIFR Swiss Prot#

P42702

LIFR Protein names

Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118)

LIFR Gene names

LIFR

Organism

Human

LIFR Entry name

LIFR_HUMAN

LIFR Codon optimized cDNA(gene) Clone

LIFR Cat #

RPV0069

Tag

LIFR contains A 6x histidine tag

LIFR Formulation

Liquid

LIFR Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

LIFR Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant LIFR Protein

LIFR Cat #

PV0069

LIFR Source

recombinant.

LIFR Applications

Western Blot, SDS-Page or may be used for other applications determined by user

LIFR Purity

>90%, as determined by SDS-PAGE under reducing conditions

LIFR Activity

N/A

Tag

LIFR Contains A 6x histidine tag

LIFR Formulation

Liquid

LIFR Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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LIFR family

SUBUNIT: Heterodimer composed of LIFR and IL6ST. The heterodimer formed by LIFR and IL6ST interacts with the complex formed by CNTF and CNTFR.

LIFR Subcellular locations

SUBCELLULAR LOCATION: Isoform 1: Cell membrane; Single-pass type I membrane protein. ; SUBCELLULAR LOCATION: Isoform 2: Secreted.

LIFR FUNCTION According to UniProtKB Swiss Prot

Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.

LIFR Sequence

DDBJ

EMBL

GenBank

LIFR 3D structure

ModBase

LIFR interaction

STRING

LIFR Proteomic

PRIDE

LIFR Genome annotation

Ensembl

GeneID

KEGG

UCSC

LIFR Organism specific

CTD

MGI

LIFR Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

LIFR Gene expression

Bgee

ArrayExpress

Genevestigator

LIFR Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY