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Mouse cd117 (aa 25 – 523)

Sl Swiss Prot#

P05532

Sl Protein names

Mast/stem cell growth factor receptor (SCFR) (EC 2.7.10.1) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (CD antigen CD117)

Sl Gene names

Kit Sl

Organism

Mouse

Sl Entry name

KIT_MOUSE

Sl Codon optimized cDNA(gene) Clone

Sl Cat #

RPV0068

Tag

Sl contains A 6x histidine tag

Sl Formulation

Liquid

Sl Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Sl Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Sl Protein

Sl Cat #

PV0068

Sl Source

recombinant.

Sl Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Sl Purity

>90%, as determined by SDS-PAGE under reducing conditions

Sl Activity

N/A

Tag

Sl Contains A 6x histidine tag

Sl Formulation

Liquid

Sl Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Sl family

SUBUNIT: Interacts with APS, MPDZ and PTPRU (By similarity).

Sl Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.

Sl FUNCTION According to UniProtKB Swiss Prot

This is the receptor for stem cell factor (mast cell growth factor). It has a tyrosine-protein kinase activity. Binding of the ligands leads to the autophosphorylation of KIT and its association with substrates such as phosphatidylinositol 3-kinase (Pi3K).

Sl Sequence

DDBJ

EMBL

GenBank

Sl 3D structure

ModBase

Sl interaction

STRING

Sl Proteomic

PRIDE

Sl Genome annotation

Ensembl

GeneID

KEGG

UCSC

Sl Organism specific

CTD

MGI

Sl Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Sl Gene expression

Bgee

ArrayExpress

Genevestigator

Sl Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY