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Human CD108 (aa 53 – 490 )

CD108 Swiss Prot#

O75326

CD108 Protein names

Semaphorin-7A (CDw108) (JMH blood group antigen) (John-Milton-Hargen human blood group Ag) (Semaphorin-K1) (Sema K1) (Semaphorin-L) (Sema L) (CD antigen CD108)

CD108 Gene names

SEMA7A CD108 SEMAL

Organism

Human

CD108 Entry name

SEM7A_HUMAN

CD108 Codon optimized cDNA(gene) Clone

CD108 Cat #

RPV0041

Tag

CD108 contains A 6x histidine tag

CD108 Formulation

Liquid

CD108 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CD108 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CD108 Protein

CD108 Cat #

PV0041

CD108 Source

recombinant.

CD108 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CD108 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CD108 Activity

N/A

Tag

CD108 Contains A 6x histidine tag

CD108 Formulation

Liquid

CD108 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CD108 family

SUBUNIT: Interacts with ITGA1 and ITGB1 (Probable). Interacts with PLXNC1.

CD108 Subcellular locations

SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Note=Detected in a punctate pattern on the cell membrane of basal and supra-basal skin keratinocytes.

CD108 FUNCTION According to UniProtKB Swiss Prot

Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.

CD108 Sequence

DDBJ

EMBL

GenBank

CD108 3D structure

ModBase

CD108 interaction

STRING

CD108 Proteomic

PRIDE

CD108 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CD108 Organism specific

CTD

MGI

CD108 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CD108 Gene expression

Bgee

ArrayExpress

Genevestigator

CD108 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY