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Rat cd104 (aa 131 – 340)

Itgb4 Swiss Prot#

Q64632

Itgb4 Protein names

Integrin beta-4 (GP150) (CD antigen CD104)

Itgb4 Gene names

Itgb4

Organism

Rat

Itgb4 Entry name

ITB4_RAT

Itgb4 Codon optimized cDNA(gene) Clone

Itgb4 Cat #

RPV0029

Tag

Itgb4 contains A 6x histidine tag

Itgb4 Formulation

Liquid

Itgb4 Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Itgb4 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Itgb4 Protein

Itgb4 Cat #

PV0029

Itgb4 Source

recombinant.

Itgb4 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Itgb4 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Itgb4 Activity

N/A

Tag

Itgb4 Contains A 6x histidine tag

Itgb4 Formulation

Liquid

Itgb4 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Itgb4 family

SUBUNIT: Heterodimer of an alpha and a beta subunit. Beta-4 associates with alpha-6. Interacts (via cytoplasmic region) with COL17A1 (via cytoplasmic region). Interacts (via cytoplasmic region) with DST isoform 3 (via N-terminus). Interacts (via cytoplasmic domain) with DST (via N-terminus). Interacts with RAC1 (By similarity).

Itgb4 Subcellular locations

SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (By similarity). Cell junction, hemidesmosome (By similarity). Note=Colocalizes with DST at the leading edge of migrating keratinocytes (By similarity).

Itgb4 FUNCTION According to UniProtKB Swiss Prot

Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility (By similarity).

Itgb4 Sequence

DDBJ

EMBL

GenBank

Itgb4 3D structure

ModBase

Itgb4 interaction

STRING

Itgb4 Proteomic

PRIDE

Itgb4 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Itgb4 Organism specific

CTD

MGI

Itgb4 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Itgb4 Gene expression

Bgee

ArrayExpress

Genevestigator

Itgb4 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY