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Human cd10 (aa 52-450)
EPN Swiss Prot#
P08473
EPN Protein names
Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10)
EPN Gene names
MME EPN
Organism
Human
EPN Entry name
NEP_HUMAN
EPN Codon optimized cDNA(gene) Clone
EPN Cat #
RPV0019
Tag
EPN contains A 6x histidine tag
EPN Formulation
Liquid
EPN Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
EPN Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant EPN Protein
EPN Cat #
PV0019
EPN Source
recombinant.
EPN Applications
Western Blot, SDS-Page or may be used for other applications determined by user
EPN Purity
>90%, as determined by SDS-PAGE under reducing conditions
EPN Activity
N/A
Tag
EPN Contains A 6x histidine tag
EPN Formulation
Liquid
EPN Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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EPN family
-
EPN Subcellular locations
SUBCELLULAR LOCATION: Cell membrane; Single-pass type II membrane protein.
EPN FUNCTION According to UniProtKB Swiss Prot
Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
EPN Sequence
DDBJ EMBL GenBank
EPN 3D structure
ModBase
EPN interaction
STRING
EPN Proteomic
PRIDE
EPN Genome annotation
Ensembl GeneID KEGG UCSC
EPN Organism specific
CTD MGI
EPN Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
EPN Gene expression
Bgee ArrayExpress Genevestigator
EPN Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY