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| Human cd10 (aa 52-450) |
| EPN Swiss Prot# | | P08473 |
| EPN Protein names | | Neprilysin (EC 3.4.24.11) (Atriopeptidase) (Common acute lymphocytic leukemia antigen) (CALLA) (Enkephalinase) (Neutral endopeptidase 24.11) (NEP) (Neutral endopeptidase) (Skin fibroblast elastase) (SFE) (CD antigen CD10) |
| EPN Gene names | | MME EPN |
| Organism | | Human |
| EPN Entry name | | NEP_HUMAN |
| EPN Codon optimized cDNA(gene) Clone |
| EPN Cat # | | RPV0019 |
| Tag | | EPN contains A 6x histidine tag |
| EPN Formulation | | Liquid |
| EPN Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| EPN Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant EPN Protein |
| EPN Cat # | | PV0019 |
| EPN Source | | recombinant. |
| EPN Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| EPN Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| EPN Activity | | N/A |
| Tag | | EPN Contains A 6x histidine tag |
| EPN Formulation | | Liquid |
| EPN Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant EPN Products | | For pricing and availability Click Here >>> |
| EPN family | | - |
| EPN Subcellular locations | | SUBCELLULAR LOCATION: Cell membrane; Single-pass type II membrane protein. |
| EPN FUNCTION According to UniProtKB Swiss Prot | | Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers. |
| EPN Sequence | | DDBJ | EMBL | GenBank |
| EPN 3D structure | | ModBase |
| EPN interaction | | STRING |
| EPN Proteomic | | PRIDE |
| EPN Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| EPN Organism specific | | CTD | MGI |
| EPN Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| EPN Gene expression | | Bgee | ArrayExpress | Genevestigator |
| EPN Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |