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STRPN Immunoglobulin A1 protease (aa 101-500)

Immunoglobulin A1 protease Swiss Prot#

Q54875

Immunoglobulin A1 protease Protein names

Immunoglobulin A1 protease (IgA1 protease) (EC 3.4.24.13) (IgA-specific zinc metalloproteinase)

Immunoglobulin A1 protease Gene names

iga

Organism

Streptococcus pneumoniae

Immunoglobulin A1 protease Entry name

IGA1B_STRPN

Immunoglobulin A1 protease Codon optimized cDNA(gene) Clone

Immunoglobulin A1 protease Cat #

RPP0961

Tag

Immunoglobulin A1 protease contains A 6x histidine tag

Immunoglobulin A1 protease Formulation

Liquid

Immunoglobulin A1 protease Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Immunoglobulin A1 protease Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Immunoglobulin A1 protease Protein

Immunoglobulin A1 protease Cat #

PP0961

Immunoglobulin A1 protease Source

recombinant

Immunoglobulin A1 protease Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Immunoglobulin A1 protease Purity

>90%, as determined by SDS-PAGE under reducing conditions

Immunoglobulin A1 protease Activity

N/A

Tag

Immunoglobulin A1 protease Contains A 6x histidine tag

Immunoglobulin A1 protease Formulation

Liquid

Immunoglobulin A1 protease Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Immunoglobulin A1 protease family

Peptidase M26 family

Immunoglobulin A1 protease Subcellular locations

Secreted > cell wall. Membrane; Multi-pass membrane protein. Secreted > cell wall; Peptidoglycan-anchor.

Immunoglobulin A1 protease FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Zinc metalloproteinase which cleaves human immunoglobulin A1 (IgA1) in the hinge region, rendering it less efficient in coating the surface of colonizing or invading pneumococci. May be responsible for pneumococcal infection and is potentially involved in distinct stages of pneumococcal disease.

Immunoglobulin A1 protease Sequence

DDBJ

EMBL

GenBank

Immunoglobulin A1 protease 3D structure

ModBase

Immunoglobulin A1 protease interaction

STRING

Immunoglobulin A1 protease Proteomic

PRIDE

Immunoglobulin A1 protease Genome annotation

Ensembl

GeneID

KEGG

UCSC

Immunoglobulin A1 protease Organism specific

CTD

MGI

Immunoglobulin A1 protease Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Immunoglobulin A1 protease Gene expression

Bgee

ArrayExpress

Genevestigator

Immunoglobulin A1 protease Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY