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STAA8 Transcriptional regulator sarA (aa 21-124)
Transcriptional regulator sarA Swiss Prot#
Q2G2U9
Transcriptional regulator sarA Protein names
Transcriptional regulator sarA (Staphylococcal accessory regulator A)
Transcriptional regulator sarA Gene names
sarA (SAOUHSC_00620)
Organism
Staphylococcus aureus (strain NCTC 8325)
Transcriptional regulator sarA Entry name
SARA_STAA8
Transcriptional regulator sarA Codon optimized cDNA(gene) Clone
Transcriptional regulator sarA Cat #
RPP0894
Tag
Transcriptional regulator sarA contains A 6x histidine tag
Transcriptional regulator sarA Formulation
Liquid
Transcriptional regulator sarA Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Transcriptional regulator sarA Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Transcriptional regulator sarA Protein
Transcriptional regulator sarA Cat #
PP0894
Transcriptional regulator sarA Source
recombinant
Transcriptional regulator sarA Applications
Western Blot, SDS-Page or may be used for other applications determined by user
Transcriptional regulator sarA Purity
>90%, as determined by SDS-PAGE under reducing conditions
Transcriptional regulator sarA Activity
N/A
Tag
Transcriptional regulator sarA Contains A 6x histidine tag
Transcriptional regulator sarA Formulation
Liquid
Transcriptional regulator sarA Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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Transcriptional regulator sarA family
SarA family
Transcriptional regulator sarA Subcellular locations
Cytoplasm.
Transcriptional regulator sarA FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Global regulator with both positive and negative effects that controls expression of several virulence factors and biofilm formation process in a cell density-dependent manner. In a strain-dependent manner plays a role in multidrug resistance mechanism. Is required for transcription of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus. Acts as a transcriptional activator of the genes encoding, among others, for fibronectin binding proteins (fnbA and fnbB), hemolysins (hla, hld, hlgB and hlgC), serine proteases (splA, splB, splD and splF) and of the bap gene, which is essential for biofilm development in some strains. Negatively regulates the expression of the genes for protein A (spa), lipase (lip), thermonuclease (nuc), immunodominant staphylococcal antigen B (isaB), staphylococcal serine and cysteine proteases (sspA and sspB), staphostatin B (sspC), metalloprotease aureolysin (aur) and collagen adhesin (cna). Probably activates the development of biofilm by both enhancing the ica operon transcription and suppressing the transcription of either a protein involved in the turnover of PIA/PNAG or a repressor of its synthesis, whose expression would be sigma-B-dependent.
Transcriptional regulator sarA Sequence
DDBJ EMBL GenBank
Transcriptional regulator sarA 3D structure
ModBase
Transcriptional regulator sarA interaction
STRING
Transcriptional regulator sarA Proteomic
PRIDE
Transcriptional regulator sarA Genome annotation
Ensembl GeneID KEGG UCSC
Transcriptional regulator sarA Organism specific
CTD MGI
Transcriptional regulator sarA Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Transcriptional regulator sarA Gene expression
Bgee ArrayExpress Genevestigator
Transcriptional regulator sarA Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY